How To Look At The Content And Hardness Of The Tablet Pressed By The Tablet Press-richpacking020.com

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How To Look At The Content And Hardness Of The Tablet Pressed By The Tablet Press

Sep 05, 2022

The consistency and uniformity of the compressed content of the tablet press rotation is not suitable. Generally, it occurs in the tableting of pellets and small doses of medicines, the main medicine or percentage: in the tableting of pellets, the size of the particles is different due to the thickness and size. , The same material and layered material are completely mixed during the granulation process, the machine vibrates, and the best solution at present is to reduce the tableting rate (the method that affects the production efficiency, but whether there is a better method to be determined).

After the migration of soluble components is completed, the granulation and drying or coating process steps, the evaporation process during drying brings some moving particles between soluble components, resulting in unqualified uniformity and consistency, but with great affinity excipients, Solubility components with excipients or microwave drying.

RPM: This can happen in a tablet press, when tablet hardness is set at low speed, and when RPM increases, tablet hardness becomes lower. If the rotation speed is too fast, the pressure time on the material will be shortened, the particles will rebound quickly, and the hardness will be reduced, so the speed of the turntable can be reduced appropriately or increased by increasing the preload.

pharma tablet press

Lubricants: Excessive use of lubricants in rotary tablet presses or excessive mixing times can weaken the bonds between the granules, thereby reducing tablet hardness. Particle size: The overall particle size is small, the specific surface area is large, and the hardness is large. Coarse particles can be tested in the granulation stage.

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