How To Solve The Problem Of Dust In The Tableting Process-richpacking020.com

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How to Solve the Problem of Dust in the Tableting Process

Jul 15, 2022

How to solve the problem of dust in the tableting process of powder Rotary tablet press.

The following is a discussion of dust issues during tablet molding.

1. Analysis of the cause of dust: At present, the dust generated in the production and operation of high-speed rotary tablet press machine and screening machines in mainland China is generally removed by using a special vacuum cleaner to provide negative pressure to remove dust. However, due to the gap between the state of the art and awareness, the sealing effect of the equipment itself is not ideal, and some dust still leaks into the decontamination area. In addition, dust generated by material handling or tablet transfer processes can also leak directly into the decontamination area from the associated joints.

2. The true degree of purification indicators: China's current GMP purification level is mainly concentrated on static indicators. In this case, the dust generated during the tableting process of small powder tableting machines is often overlooked. In other countries or regions, the indicators are dynamically detected during the actual production process, and the release of dust will directly affect the number of dust particles in the work area. Obviously, the latter test data is more realistic. China's new version of GMP mainly refers to the revision of EU GMP, and the detection and evaluation of purification indicators after the implementation of the new standard should meet the standard.

3. Solution; in order to reduce the amount of dust leakage during the tablet pressing process of the rotary tablet press, the protection level of the equipment should be improved; the pharmaceutical company should clearly specify the specific sealing and isolation requirements of the equipment supplier, and the isolation measures provided Make a reasonable assessment.

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