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Testing Requirements For Blister Packaging

Testing Requirements For Blister Packaging

Oct 24, 2021
Testing requirements for blister packaging machine


blister packing machine


The primary packaging tool of blister packaging is solid medicines. The packaging should isolate the contained pharmaceutical preparations from the outside world, on the one hand, to avoid the volatilization, escape and leakage of the active ingredients of the medicine. Volatile pharmaceutical ingredients can ablate on the inside of the packaging material and disperse to the other side under the use of osmotic pressure. For example, solid pharmaceutical preparations containing aromatic ingredients and volatile active ingredients, the active ingredients are volatile and penetrate certain Some materials.


On the other hand, avoid the outside air, water, foreign matter, and microorganisms from entering and contact with medicines. The air contains oxygen, water, a large number of microorganisms and foreign particles. These ingredients will cause oxidation, hydrolysis, degradation, purification and fermentation of medicines after entering the packaging.

The PTP aluminum foil and PVC hard film or PVC/PVDC composite hard film used in blister packaging will directly contact the medicine. Therefore, special attention must be paid to the inspection of the material. The inspection items include appearance, insidious function, higher tensile strength, and shock resistance, heat resistance Mechanical functions such as tightening rate, and hygiene goals, etc. Recognize that there are corresponding testing methods and specifications (or corporate specifications).


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